Multiple Endocrine Neoplasia Type 1

A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).

Also Known As:

Multiple Endocrine Neoplasia Type I; Multiple Endocrine Neoplasms Type 1; Neoplasms, Multiple Endocrine Type I; Neoplasia, Multiple Endocrine Type 1; Neoplasms, Multiple Endocrine Type 1; Wermer Syndrome

Neoplasms: 1324753
- Hereditary Neoplastic Syndromes: 112
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 1: 535
- Multiple Primary Neoplasms: 24
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 1: 535
- Neoplasms by Site: 4
  - Endocrine Gland Neoplasms: 130
    - Multiple Endocrine Neoplasia: 504
      - Multiple Endocrine Neoplasia Type 1: 535
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Hereditary Neoplastic Syndromes: 112
    - Multiple Endocrine Neoplasia: 504
      - Multiple Endocrine Neoplasia Type 1: 535
Endocrine System Diseases: 968
- Endocrine Gland Neoplasms: 130
  - Multiple Endocrine Neoplasia: 504
    - Multiple Endocrine Neoplasia Type 1: 535

J J Shepherd Selected Research

J J Shepherd Research Topics

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